Phage-Targeting PCR Test Picks Up Early Lyme Disease

An investigational polymerase chain reaction (PCR) test that detects the presence of a viral gene in Lyme disease–causing bacteria can distinguish... View Article

Detection of Babesia odocoilei in Ixodes scapularis Ticks Collected in Southern Ontario, Canada

Abstract Tick-borne zoonotic diseases have an economic and societal impact on the well-being of people worldwide. In the present study,... View Article

Study Suggests Similar Processes Are Driving Long COVID and ME/CFS [and Lyme disease]

Mar 12, 2021 “Similar disease signatures to ME/CFS showed up for diseases like MIS-C, Lyme disease, and COVID-19 but not... View Article

Botanical Medicines Cryptolepis sanguinolenta, Artemisia annua, Scutellaria baicalensis, Polygonum cuspidatum, and Alchornea cordifolia Demonstrate Inhibitory Activity Against Babesia duncani

Front. Cell. Infect. Microbiol., 08 March 2021 | https://doi.org/10.3389/fcimb.2021.624745 “Human babesiosis is a CDC reportable disease in the United States and... View Article

HHS Aims to Accelerate Technologies for Combatting Lyme Disease – Chief scientist tells of her several year battle with Lyme disease

Published March 5th, 2021 at Nexgov.com authored by Brandi Vincent “Then I got what I thought was the summer flu.... View Article

Borrelia miyamotoi-An Emerging Human Tick-Borne Pathogen in Europe

[CanLyme Note: Canada has Borrelia miyamotoi coast to coast in ticks.] January 12, 2021 Abstract Borrelia miyamotoi is classified as a relapsing... View Article

Bartonella henselae Neuroretinitis: A Rare Coinfection in POEMS Syndrome

Abstract Bartonella henselae is a recognized cause of neuroretinitis in cat scratch disease. Meanwhile, polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, skin... View Article

New Podcast: Dr. Theoharis Theoharides, Professor of Immunology at Tufts University School of Medicine in Boston.

Welcome back! Season 2 of the Looking at Lyme podcast starts now. Dr. Theoharides has been on the leading edge... View Article

Borrelia burgdorferi-Induced Changes in the Class II Self-Immunopeptidome Displayed on HLA-DR Molecules Expressed by Dendritic Cells

September 2020 The MHC class II antigen processing and presentation pathway has evolved to derive short amino acid peptides from... View Article

Phase 4 Block of the Right Bundle Branch Suggesting His-Purkinje System Involvement in Lyme Carditis

[CanLyme Note: As new research unfolds we are discovering that borrelia other than Borrelia burgdorferi (Bb) are pathogenic to humans. Much research... View Article

Evaluation of pathogen specific urinary peptides in tick-borne illnesses

Abstract Mass spectrometry enhanced by nanotechnology can achieve previously unattainable sensitivity for characterizing urinary pathogen-derived peptides. We utilized mass spectrometry... View Article

Canada: Microbiome Composition and Borrelia Detection in Ixodes scapularis Ticks at the Northwestern Edge of Their Range

Abstract Lyme disease-causing Borrelia burgdorferi has been reported in 10–19% of Ixodes ticks from Alberta, Canada, where the tick vector Ixodes scapularis is at the northwestern... View Article

Will this latest Canadian research change the paradigm of testing and lab diagnostics for Lyme disease globally?

Abstract Serological diagnosis of Lyme disease suffers from considerable limitations. Yet, the technique cannot currently be replaced by direct detection... View Article

YebC regulates variable surface antigen VlsE expression and is required for host immune evasion in Borrelia burgdorferi

Oct. 2020 PLOS PATHOGENS Abstract Borrelia burgdorferi, the Lyme disease pathogen causes persistent infection by evading the host immune response.... View Article

New Podcast: Back to the lab with Dr. Melanie Wills from the G. Magnotta Lyme Disease Research Lab at the University of Guelph

“In this episode Sarah talks research, Canadian research that is, with Dr. Melanie Wills. She is the Director of the... View Article

Unintended Consequences: The Perils of Publication and Citation Bias

“The system of scientific communication appears to be more fragile than was once believed.” Decisions made by individuals with particular... View Article

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