How to Remove a Tick
Categories for Research
Another tick borne disease to guard against. [already in Canada]
Despite its many delights, summer also brings its fair share of pestilence. One, called babesiosis, has only recently been widely... View Article
Persistence of Borrelia burgdorferi in Rhesus Macaques following Antibiotic Treatment of Disseminated Infection.
“Our studies do however offer proof of the principle that intact spirochetes can persist in an incidental host comparable to... View Article
Vector competence of the tick Ixodes ricinus for transmission of Bartonella birtlesii
PLoS Negl Trop Dis. 2011;5(5):e1186. Epub 2011 May 31. Reis C, Cote M, Le Rhun D, Lecuelle B, Levin ML,... View Article
Borrelia Burgdorferi Evades the Effects of Ceftriaxone Treatment in a Mouse Model of Lyme Borreliosis
Lyme borreliosis (LB) is a tick-borne infectious disease with variable symptoms. The most common manifestation of LB is an expanding rash on the skin but frequently arthritic or neurological and occasionally cardiac or ocular symptoms are seen.
Lyme borreliosis in Canada: biological diversity and diagnostic complexity from an entomological perspective
Lyme borreliosis (LB), also known as Lyme disease, is emerging as a serious tick- borne illness across Canada. More than three decades of research on LB in North America and Europe have provided a large, complex body of research involving well-documented difficulties at several levels.
Real-Time High Resolution 3D Imaging of the Lyme Disease Spirochete Adhering to and Escaping from the Vasculature of a Living Host
Pathogenic spirochetes are bacteria that cause a number of emerging and re-emerging diseases worldwide, including syphilis, leptospirosis, relapsing fever, and Lyme borreliosis
HrpA, a DEAH-Box RNA Helicase, Is Involved in Global Gene Regulation in the Lyme Disease Spirochete
Spirochetes causing Lyme borreliosis are obligate parasites that can only be found in a tick vector or a vertebrate host. The ability to survive in these two disparate environments requires up and downregulation of specific genes by regulatory circuits that remain largely obscure.
Investigation of the genes involved in antigenic switching at the vlsE locus in Borrelia burgdorferi: an essential role for the RuvAB branch migrase.
Persistent infection by pathogenic organisms requires effective strategies for the defense of these organisms against the host immune response.
An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells
Here we investigate the dynamics of the hepatic intravascular immune response to a pathogen relevant to invariant natural killer T cells (iNKT cells).
Detection of Lyme disease spirochete, Borrelia burgdorferi sensu lato, including three novel genotypes in ticks (Acari: Ixodidae) collected from songbirds (Passeriformes) across Canada
The source of sporadic Lyme disease (Lyme borreliosis) across Canada has been a mystery. Several tenets abound about the origin of this bacterial illness, but science is often lacking.
Widespread dispersal of Borrelia burgdorferi-infected ticks collected from songbirds across Canada.
Scott JD, Anderson JF, Durden LA J Parasitol 2011 08 24 Abstract Millions of Lyme disease vector ticks are dispersed... View Article
Genetic blueprint of bacteria causing Lyme disease unraveled
Benjamin Luft, M.D., Professor of Medicine, Stony Brook University Medical Center, and a team of medical researchers have determined the genetic blueprint of 13 strains of the bacteria that cause Lyme disease. The finding is crucial to advancing research on Lyme disease, the most frequent tick-borne infection in North America and Europe, and may lead to better diagnostics and a vaccine
Whole-Genome Sequences of Thirteen Isolates of Borrelia burgdorferi
Borrelia burgdorferi is a causative agent of Lyme disease in North America and Eurasia. The first complete genome sequence of B. burgdorferi strain 31, available for more than a decade, has assisted research on the pathogenesis of Lyme disease.
CSM Murray Award Lecture – Functional studies of the Lyme disease spirochete – from molecules to mice
Department of Biochemistry & Molecular Biology, and Department of Microbiology & Infectious Diseases, University of Calgary
Metagenomic Profile of the Bacterial Communities Associated with Ixodes ricinus Ticks.
Assessment of the microbial diversity residing in arthropod vectors of medical importance is crucial for monitoring endemic infections, for surveillance of newly emerging zoonotic pathogens, and for unraveling the associated bacteria within its host.