Estimating the Frequency of Lyme Disease Diagnoses, United States, 2010–2018

Abstract By using commercial insurance claims data, we estimated that Lyme disease was diagnosed and treated in ≈476,000 patients in... View Article

Mothers Against Lyme: Request for Correction of Factual Error in IDSA/AAN/ACR 2020 Guidelines for Prevention, Diagnosis and Treatment of Lyme Disease

[Canlyme Note: The Lyme disease guidelines of the IDSA, AAN, and ACR are simply a further example of their continued assault... View Article

The Platelet Fraction Is a Novel Reservoir to Detect Lyme Borrelia in Blood

October 29th, 2021 Victoria P Sanderson 1, Iain L Mainprize 1, Lisette Verzijlenberg 1, Cezar M Khursigara 2, Melanie K B Wills 1 Abstract Serological diagnosis of Lyme disease... View Article

The peptidoglycan-associated protein NapA plays an important role in the envelope integrity and in the pathogenesis of the lyme disease spirochete

Abstract The bacterial pathogen responsible for causing Lyme disease, Borrelia burgdorferi, is an atypical Gram-negative spirochete that is transmitted to... View Article

Harvard study identifies symptom clusters in Lyme patients with persistent symptoms

A retrospective study of 270 post-treatment Lyme patients identified the most debilitating neurological symptoms, paving the way for future studies on root... View Article

Evidence-Based, Patient-Centered Treatment of Erythema Migrans in the United States

Abstract Lyme disease, often characterized as a readily treatable infection, can be a debilitating and expensive illness, especially when patients... View Article

Detection of Babesia odocoilei in Humans with Babesiosis Symptoms

Abstract Human babesiosis is a life-threatening infectious disease that causes societal and economic impact worldwide. Several species of Babesia cause babesiosis in... View Article

Detecting Borrelia Spirochetes: A Case Study With Validation Among Autopsy Specimens

The complex etiology of neurodegenerative disease has prompted studies on multiple mechanisms including genetic predisposition, brain biochemistry, immunological responses, and... View Article

Botanical Medicines Cryptolepis sanguinolenta, Artemisia annua, Scutellaria baicalensis, Polygonum cuspidatum, and Alchornea cordifolia Demonstrate Inhibitory Activity Against Babesia duncani

Front. Cell. Infect. Microbiol., 08 March 2021 | https://doi.org/10.3389/fcimb.2021.624745 “Human babesiosis is a CDC reportable disease in the United States and... View Article

ALS or ALS mimic by neuroborreliosis—A case report

[CanLyme Note: This report relates that their is reason to double check positive CSF PCR tests for Lyme disease. There is... View Article

Borrelia miyamotoi-An Emerging Human Tick-Borne Pathogen in Europe

[CanLyme Note: Canada has Borrelia miyamotoi coast to coast in ticks.] January 12, 2021 Abstract Borrelia miyamotoi is classified as a relapsing... View Article

Borrelia burgdorferi-Induced Changes in the Class II Self-Immunopeptidome Displayed on HLA-DR Molecules Expressed by Dendritic Cells

September 2020 The MHC class II antigen processing and presentation pathway has evolved to derive short amino acid peptides from... View Article

Phase 4 Block of the Right Bundle Branch Suggesting His-Purkinje System Involvement in Lyme Carditis

[CanLyme Note: As new research unfolds we are discovering that borrelia other than Borrelia burgdorferi (Bb) are pathogenic to humans. Much research... View Article

Will this latest Canadian research change the paradigm of testing and lab diagnostics for Lyme disease globally?

Abstract Serological diagnosis of Lyme disease suffers from considerable limitations. Yet, the technique cannot currently be replaced by direct detection... View Article

Lyme Disease Patient Outcomes and Experiences; A Retrospective Cohort Study

Abstract Lyme disease is a vector-borne illness caused by Borrelia spp. bacterium spread by ticks to humans and other mammals. Despite being... View Article

Fatal Lyme carditis presenting as fluctuating high-grade atrioventricular block

RE: Lyme carditis and neuroborreliosis Edward J Cormode [MD, FRCP], Retired paediatrician, Canadian Medical Association The three cases presented in the “Practice “section of... View Article

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