Author Archives for jen

Borrelia Burgdorferi Evades the Effects of Ceftriaxone Treatment in a Mouse Model of Lyme Borreliosis

July 21, 2012 2:01 pm Published by Comments Off on Borrelia Burgdorferi Evades the Effects of Ceftriaxone Treatment in a Mouse Model of Lyme Borreliosis

Lyme borreliosis (LB) is a tick-borne infectious disease with variable symptoms. The most common manifestation of LB is an expanding rash on the skin but frequently arthritic or neurological and occasionally cardiac or ocular symptoms are seen.


Lyme borreliosis in Canada: biological diversity and diagnostic complexity from an entomological perspective

July 21, 2012 1:58 pm Published by Comments Off on Lyme borreliosis in Canada: biological diversity and diagnostic complexity from an entomological perspective

Lyme borreliosis (LB), also known as Lyme disease, is emerging as a serious tick- borne illness across Canada. More than three decades of research on LB in North America and Europe have provided a large, complex body of research involving well-documented difficulties at several levels.


HrpA, a DEAH-Box RNA Helicase, Is Involved in Global Gene Regulation in the Lyme Disease Spirochete

July 21, 2012 1:52 pm Published by Comments Off on HrpA, a DEAH-Box RNA Helicase, Is Involved in Global Gene Regulation in the Lyme Disease Spirochete

Spirochetes causing Lyme borreliosis are obligate parasites that can only be found in a tick vector or a vertebrate host. The ability to survive in these two disparate environments requires up and downregulation of specific genes by regulatory circuits that remain largely obscure.


Detection of Lyme disease spirochete, Borrelia burgdorferi sensu lato, including three novel genotypes in ticks (Acari: Ixodidae) collected from songbirds (Passeriformes) across Canada

July 21, 2012 1:43 pm Published by Comments Off on Detection of Lyme disease spirochete, Borrelia burgdorferi sensu lato, including three novel genotypes in ticks (Acari: Ixodidae) collected from songbirds (Passeriformes) across Canada

The source of sporadic Lyme disease (Lyme borreliosis) across Canada has been a mystery. Several tenets abound about the origin of this bacterial illness, but science is often lacking.


Genetic blueprint of bacteria causing Lyme disease unraveled

July 21, 2012 1:38 pm Published by Comments Off on Genetic blueprint of bacteria causing Lyme disease unraveled

Benjamin Luft, M.D., Professor of Medicine, Stony Brook University Medical Center, and a team of medical researchers have determined the genetic blueprint of 13 strains of the bacteria that cause Lyme disease. The finding is crucial to advancing research on Lyme disease, the most frequent tick-borne infection in North America and Europe, and may lead to better diagnostics and a vaccine